Bachem/淀粉样β-蛋白（4-42）铵盐/H-7434.0500/0.5 mg
商品编号：
H-7434.0500
品牌：
巴亨
市场价：
¥9420.00
美元价：
5652.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Details
Aβ 4-42 could be one of the earliest and most prominent Aβ species deposited in AD brain. Sequencing of amyloid plaque cores showed that 64% of the isolated Aβ had a phenylalanine at its N-terminus, and indeed, IP/MS experiments identified Aβ 4-42 as a major Aβ species in AD patients. Additionally, Aβ 4-42 was found to be a component of cotton wool plaques in familial AD patients with the V261I PS1 mutation. Aβ 4-42 was discovered as well in amyloid deposits from vascular dementia and familial Danish dementia patients. These observations indicate that Aβ 4-42 may contribute to the development of multiple CNS diseases.
Item Number
4090138
One Letter Code
FRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Synonyms
Aβ (4-42)
Molecular Formula
C₁₉₁H₂₉₄N₅₂O₅₃S
Relative Molecular Mass
4198.82
CAS Registry Number
[157884-72-5] net
Source
Synthetic
Storage Conditions
-20 ± 5 °C
Areas of Interest
Alzheimer's Disease
Links / Documents:
- Peptide Calculator
Brochures:
- Amyloid Peptides
- Care and Handling of Amyloid Peptides
Product citations
G. Antonios et al.,
Acta Neuropathol. Commun.,
1,
56 (2013)
Y. Bouter et al.,
Acta Neuropathol.,
126,
189 (2013)
E.Portelius et al.,
Acta Neuropathol.,
120,
185 (2010)
Y. Tomidokoro et al.,
J. Biol. Chem.,
280,
36883 (2005)
品牌介绍
瑞士Bachem（巴亨）多肽
